The neck is swollen, soft and elastic, and moves up and down when swallowing, which may also cause the vocal cords to be squeezed and become vocal; the patient’s eyes may feel swollen and even become protruding from the orbits, forming proptosis. Patients are afraid of heat, sweating, damp skin, and may develop hypothermia; they begin to become easily hungry, grow in food intake, have more frequent bowel movements, and lose weight. There will be panic, palpitations, increased heart rate, and in severe cases, atrial fibrillation; easily agitated, excited, talkative, active, and insomnia; many patients feel tired, weak, and easily fatigued; irregular menstruation and decreased fertility.