Trigeminal neuralgia, known as the “number one pain in the world”, has caused many patients to suffer from it. The symptoms of trigeminal neuralgia are often reflected in the severe pain in the face, because the face is an important distribution area of the trigeminal nerve, the disease onset of the facial trigeminal nerve distribution area paroxysmal severe pain, pain will bring great impact on the life of patients, not only affect their physical health, but also a kind of mental torture. How can trigeminal neuralgia be treated effectively? Drug treatment is the most commonly used treatment method for trigeminal neuralgia, many patients in the beginning of the use of carbamazepine, the treatment effect is okay, can temporarily relieve pain, with the delay of time, drug resistance, the treatment effect is getting worse and worse, the side effects are more and more obvious, at this time, patients take drugs to increase the amount or switch to other drugs, oxcarbazepine, phenytoin sodium, etc., if still can not effectively control If the pain is still not effectively controlled, surgery needs to be considered early. The three most popular surgical treatments for trigeminal neuralgia are radiofrequency thermal coagulation, gamma knife and microvascular decompression. For the characteristics of these three kinds of surgery, Professor Zhang Qingbin said that microvascular decompression is an open surgery, which requires patients to be in good health and must be able to tolerate the surgery, and costs more, usually tens of thousands of dollars. In addition, sometimes the complications of microvascular decompression are more serious, and there have been reports of deaths at home and abroad; Gamma Knife is a bloodless surgery, without anesthesia and special preparation. Apparently non-invasive treatment, but in fact the potential trauma of the gamma knife should not be underestimated. Gamma knife is a radioactive killing treatment, where the normal tissue and lesion tissue in the irradiated area, all kill, the greater the irradiation range, the longer the irradiation time, the greater the killing of normal tissue, especially to the vital organs, the blow more; Gamma knife in the irradiation or after the irradiation will also cause a series of radiation reactions, such as hair loss, nausea and vomiting, weakness. Some patients with gamma knife treatment, the pain disappears quickly. However, it lasts for a short period of time and recurs within a few months, which may be related to low immune function. This procedure is generally not used by patients and is now gradually being phased out. Radiofrequency thermocoagulation is a minimally invasive procedure with a high degree of safety, using the different temperature tolerance of different nerve fibers to selectively “destroy” the nerve fibers that transmit pain, leaving other nerve fibers unaffected. This method can be performed under local anesthesia without surgery, and the pain relief effect is immediate, especially for elderly patients who are not suitable for or do not tolerate open surgery; the cure rate of this procedure is about 95%, which is the first choice of treatment for trigeminal neuralgia at present.