Some patients with fatty liver disease experience pain in the upper right abdomen. If the patient has a history of liver disease or a family history of liver disease, it is necessary to go to the hospital as soon as possible after the appearance of right upper abdominal pain. The body surface shadowing area of the liver is the right quadrant of the ribs, and although there is no nerve distribution within the cellular tissue of the liver, the liver peritoneum is rich in nerves. When the liver cells are infiltrated by fat, the liver becomes enlarged, and the hepatic peritoneum is then overstretched, causing distension and pain in the right upper abdomen. The pain may become more pronounced during exercise. In addition to this, patients with fatty liver may also experience loss of appetite, fatigue and splenomegaly. If fatty liver is not treated actively, it may develop into cirrhosis and liver cancer. It is recommended that patients go to the hospital as soon as possible and actively cooperate with the doctor to prevent the condition from developing and affecting the therapeutic effect.