Once severe acute pancreatitis occurs, the disease develops rapidly and evolves in a complex manner, with high complication rates, morbidity and mortality rates, and medical costs. It is very important for doctors to identify early, active and effective resuscitation to stop the progression of the disease. Below I give you an analysis of the key aspects of success or failure in resuscitation of severe acute pancreatitis, which may have some reference value for you. A, the reasons for failure 1, the evolution of severe acute pancreatitis complex, many complications, rapid development, multi-organ failure within a short period of time (a few hours), giving doctors less opportunity to examine and resuscitate, the patient died quickly, that is, the outbreak of severe acute pancreatitis. 2. Patients with moderate onset of disease are easily neglected, and their condition suddenly worsens during the treatment process, and doctors and families do not pay attention to it, especially during weekends or holidays, and wait for further deterioration before actively rescuing them. 3, surgery indications are not strict, early onset of emergency surgery, or biliary source of severe acute pancreatitis is missed, and severe acute pancreatitis is found only during gallbladder surgery; postoperative infection, bleeding and multi-organ failure cannot be corrected, and the patient’s family has no financial ability to continue treatment and give up on life. 4. Patients with abdominal pain were not examined for clear diagnosis, treated with infusion in small hospitals, and then transferred to higher level hospitals for treatment when their condition worsened, losing the opportunity for early resuscitation. Second, the successful experience 1, the mind attaches great importance to the severe abdominal pain or abdominal pain cause is not clear, should be a comprehensive examination, early clear diagnosis. 2, previous history of biliary source of severe acute pancreatitis, gallbladder stones, each acute attack of gallbladder stones, we should think about the possibility of complications of acute pancreatitis, should do the examination related to acute pancreatitis to clarify the diagnosis. 3, early stage of severe acute pancreatitis is difficult to distinguish from mild acute pancreatitis, especially the imaging and blood biochemical examination in early mild changes, which can be easily overlooked. Therefore, dynamic examination and close observation of changes in symptoms and signs are needed for early diagnosis and early treatment. 4, once the diagnosis of severe acute pancreatitis, must be hospitalized in a large hospital specialized ward, do not take a chance, but once the loss of early resuscitation opportunities, may be lifelong regrets, namely pain, money, life? Please remember, there is never a regret medicine in the world, there is only one life, never cherish life. 5, the key to early treatment: rapid correction of internal environmental disorders, namely early fluid resuscitation, electrolyte disorders, acid-base balance imbalance, hyperglycemia, hyperlipidemia, etc.; at the same time, rapid Chinese medicine Tongli attack, clear heat and detoxification, in order to reduce endotoxin absorption, reduce systemic inflammatory response, reduce intra-abdominal hypertension, so as to stop the development of the disease. 6, other adjuvant treatment: antibiotics to prevent infection, growth inhibitors, proton pump inhibitors, nutritional support, blood purification, ICU life support, etc. if necessary. 7.Early dynamic assessment of changes in condition and treatment effect, at least 4 times a day until the condition is stable. The purpose of assessment is to detect problems in time, adjust the treatment plan in time, and nip the disease in the bud. 8.Principles: early, accurate, hard and stable.