Diagnosis and treatment of late-onset hypogonadism (LOH): 1. What is male menopausal syndrome? What are the symptoms? After men enter the age of 40, testosterone levels in the body will decline with age, resulting in symptoms such as hot flashes, depression, irritability, as well as mental and psychological symptoms such as loss of concentration, anxiety, restlessness, temper tantrums and depression, commonly known as “male menopause”. Medically known as late-onset hypogonadism (LOH). 2.The susceptible group of LOH? Research results show that: men over 40 years old are the high prevalence of LOH; total serum testosterone declines at a rate of 1.6% per year after the age of 40, which means a decline of about 17% in 10 years. About 40% of middle-aged and older men may experience menopausal symptoms to varying degrees. However, most people still have misconceptions or blind spots about this. 3.How is LOH diagnosed and treated? In order to help middle-aged and older men detect LOH early, experts from the Chinese Medical Association’s Men’s Branch jointly recommend the internationally accepted androgen deficiency in middle-aged and older men (ADAM) self-assessment chart, which should alert men after the age of 40 to whether they have entered menopause if they experience frequent nervousness or depression, easy fatigue, memory loss, poor concentration, insomnia, decreased libido and erectile dysfunction. You can use the ADAM chart to test yourself. Attachment: Testosterone deficiency questionnaire for middle-aged and elderly men (ADAM scale) 1. 2. Is there a decrease in physical performance? 3.Is there a decrease in physical strength and/or endurance? 4.Is there a decrease in height? 5. Is there a decrease in enjoyment of life? 6.Is there any sadness and (or) bad temper? 7.Do you have erectile dysfunction? 8.Is there a recent decline in physical activity? 9.After meals, do you like to doze off? 10. Has work performance been poor recently? Evaluation: Answer “yes” or “no” to each question, and answer “yes” to question 1 or question 7 or any other 3 questions is a positive answer, the initial suspicion of LOH may be It is necessary to consult a doctor. Once the questionnaire is positive, you should go to a regular male hospital to have your testosterone level tested. If the testosterone level in the body is lower than the standard value, active and professional treatment measures should be taken under the guidance of the doctor to achieve early detection and correct diagnosis and treatment. Among them, testosterone supplementation therapy is to alleviate the physiological changes and clinical symptoms caused by partial testosterone deficiency through exogenous supplementation of testosterone, which can effectively treat LOH and improve the quality of life.