Although an occasional sleep apnea can cause some transient changes in the body, but will not cause much harm to human health, however, this kind of asphyxia recurring for a long time, night after night, year after year, the harm is not to be taken lightly. First, the cardiovascular system: 1, hypertension: 40% to 60% of patients with obstructive sleep apnea syndrome have a history of hypertension, unlike other hypertensive patients, their blood pressure is mostly highest in the morning, early morning headache, dizziness is obvious, the effect of simple drug treatment is poor. After effective treatment of apnea, hypertension can fall, and in some cases, even to the normal range. 2, pulmonary heart disease, right heart failure: pulmonary hypertension, 10% to 20% of sleep apnea syndrome patients will develop pulmonary hypertension, the prevalence of pulmonary hypertension in patients with moderate and severe sleep apnea syndrome can reach 55%, in combination with lung disorders (such as chronic bronchitis, emphysema), sleep apnea is more likely to lead to increased pulmonary artery pressure, increasing the workload of the right ventricle and right atrium and Pulmonary heart disease, right heart failure, mainly manifested as leg swelling, shortness of breath. 3, the left heart function changes: echocardiography and autopsy hair view, long-term occurrence of sleep apnea can make the left heart weight increase, ventricular wall thickening, the heart per beat ejection of blood volume decreased. 4, ischemic heart disease: ischemic heart disease mainly includes angina pectoris, myocardial infarction, and hypoxia is an important cause of angina pectoris. Studies have shown that one of the risk factors for the development of sleep apnea heart disease. The occurrence of ST-segment drop during sleep in patients with sleep apnea syndrome is very award prosperous, suggesting cardiac ischemia and hypoxia, according to the dynamic electrocardiogram. Especially in patients with pre-existing heart disease, hypoxia caused by apnea, autonomic dysfunction, combined with hypertension and other factors will accelerate the development of atherosclerosis, triggering angina pectoris and even myocardial infarction. 5, arrhythmia: sleep apnea syndrome patients sleep with alternating fast and slow heart rate, heart rate fluctuations, mostly sinus tachycardia, but also short bursts of atrial or ventricular tachycardia, slow heart conduction block, cardiac arrest, almost half of the sleep apnea syndrome patients will have a variety of arrhythmias, some even fatal. Monotherapy of sleep apnea can often achieve good results. However, it is easy to be misdiagnosed as heart disease and mismanaged. Second, the nervous system: 1, cerebrovascular disease: we all know that cerebrovascular accidents, commonly known as strokes, occur at night, and overnight, the patient will have a distorted mouth and eyes and paralyzed limbs. Studies have shown that snoring and apnea during sleep can increase the morbidity and mortality of cerebrovascular disease, more than 53% of male cerebrovascular patients have a history of long-term habitual snoring, 35% of patients with cerebrovascular accidents occur during sleep, and snoring. and apnea are closely related. More and more evidence shows that snoring and apnea is an independent risk factor for cerebrovascular disease, and has a very important role in the occurrence and aggravation of cerebrovascular accidents. 2, excessive sleepiness: frequent awakening caused by sleep apnea can seriously disrupt the patient’s sleep, and the deep sleep period is reduced or even disappears, and the patient is in a state of long-term sleep deprivation. The severity of daytime sleepiness is closely related to the severity of sleep apnea syndrome. Daytime sleepiness and drowsiness can seriously affect work, study and life, especially for drivers and patients engaged in overhead work, the accident rate is high and can endanger the lives of others. 3, mental and psychological hazards: mental retardation, personality and behavior abnormalities, and sleep apnea syndrome relationship has been very clear: sleep apnea syndrome patients with family members, colleagues, interpersonal relations are often less harmonious: depression and other psychiatric disorders can also be seen in sleep apnea syndrome patients: some studies have also found that sleep apnea now Alzheimer’s disease also has a certain relationship. Third, the endocrine metabolic system: hypoactive sexual desire or impotence in men with sleep apnea syndrome is more common. Statistics show that 50 cases of sleep and people with apnea syndrome, 44% of the patients have varying degrees of sexual dysfunction, and recent research also shows that endocrine metabolic disorders caused by sleep apnea can aggravate obesity. Fourth, the blood system: many patients with sleep apnea syndrome increased red blood cells, hemoglobin greater than 160 grams per liter, more than the normal range, increased blood viscosity, which is due to long-term apnea caused by hypoxia, the blood of red blood cells in order to carry more oxygen and compensatory hyperplasia, other endocrine hormone content changes in the body and the increase in urination caused by blood concentration and other factors are also The increase of red blood cells in the blood is an important factor. Fifth, the kidney function: sleep apnea syndrome patients increase the amount of urine during sleep at night, the number of times up to three or more, some patients increased protein content in the urine.