Wake up in the morning heart pain, may be related to heart disease, digestive system diseases, respiratory system diseases, mental and psychological diseases and other reasons. 1. Heart disease: such as angina pectoris, due to coronary artery spasm, can cause myocardial ischemia, the symptoms of heart pain in the morning. 2. Digestive system diseases: such as reflux esophagitis, acid reflux, heartburn symptoms can occur in the morning, can cause heart pain. 3. Respiratory diseases: such as pleurisy, due to the stimulating effect of inflammation, heart pain in the morning may occur. 4. Psychosomatic diseases: such as cardiac dysfunction, which may present symptoms such as panic, pain in the precordial area and chest tightness. It is recommended that people who have frequent episodes of heart pain in the morning or continue to be unrelieved go to the hospital in time to clarify the cause of the disease, and standardize the treatment under the guidance of the doctor.