Usually, the medications used to treat frigidity in women are estradiol, methyltestosterone, fluoxetine, and phentolamine. Frigidity belongs to a kind of sexual dysfunction. Usually, for female patients suffering from frigidity, estrogenic drugs such as estradiol valerate and ethinyl estradiol need to be applied under the guidance of doctors. Secondly, when menopausal women suffer from frigidity, androgenic drugs such as methyltestosterone can be used in combination, which has a certain alleviating effect. Next, patients also need to apply antidepressants such as fluoxetine, trazodone, bupropion, and alpha-adrenergic receptor blockers such as phentolamine as prescribed by the doctor. In addition to medication, clinical treatment of frigidity also needs to take psychotherapy, which includes cognitive therapy, behavioral therapy, psychoanalytic therapy and so on. To summarize, patients with frigidity need to go to the hospital in time, actively cooperate with the doctor to carry out standardized treatment, strengthen the management of daily life, maintain a good mood, and follow up on time.