HPV58 infection is a high-risk HPV infection that can lead to precancerous lesions in the cervix and even cervical cancer if it persists. It takes about two years from the beginning of infection to the occurrence of low-grade cervical lesions, and about two years to transform from low-grade to high-grade lesions, and about two years to transform from high-grade in to cervical cancer. From high-risk HPV infection to cervical cancer, it takes about 6-8 years clinically, so it is very important for women to be screened for cervical cancer. If high-risk HPV infection is found, colposcopy should be done first to exclude cervical epithelial lesions, and appropriate treatment should be given according to the results, so as to eliminate the occurrence of cervical cancer.