In a broad sense, women from birth to 18 years of age with abnormalities in the reproductive system can be seen in the pediatric gynecology clinic. For example, abnormal development of the external genitalia, such as hymenal atresia, clitoral hypertrophy, vaginal atresia, etc., found during infancy, should be examined by the pediatric gynecology department as soon as possible to find out if there are any abnormalities in the internal genitalia. Some infants are born with normal vulva, but around 3 or 4 months to 2 years old, the vestibule is closed and the vaginal urethral opening is covered, so parents often mistake it for the absence of vagina; some parents find that their children have a thin urine stream or bifurcated urine line, cry when urinating, or scratch their vulva with their hands. Pre-pubescent girls with red, swollen, itchy vulva and purulent discharge should be seen in time for possible vulvovaginitis in young girls. If there is unexplained vaginal bleeding, she should undergo a routine pediatric gynecologic examination to exclude common vaginal foreign bodies and, rarely, vaginal malignancies. In prepubescent girls with persistent vulvar itching, pale, atrophic or rough and cracked mucous membrane, which does not improve with the usual methods of external washing, they should be examined by a pediatric gynecologist and, if necessary, a skin biopsy should be performed to clarify the diagnosis. If a teenage girl has vulvar itching with milky or bean curd-like vaginal discharge, she should have her vaginal secretions examined for possible fungal vaginitis. Menstrual disease in adolescent girls is also a common disease in pediatric gynecology. The first menstruation is a sign of pubertal development, but does not mean maturity. We need to clarify the normal menstrual cycle, which is generally 28±7 days, that is, between 21 and 35 days are normal; with periods of 3 to 7 days is normal. It is recommended to consult a doctor when one of the following conditions occurs: menstrual cycle is still abnormal 2-3 years after menarche; menopause for more than 3 months, accompanied by obesity, excessive hair growth, acne; prolonged menstrual period; excessive menstrual volume, anemia such as dizziness, weakness, shortness of breath after one menstrual period; age 14 years old without secondary sexual characteristics; age 16 years old without menstruation, with or without secondary sexual characteristics All patients should seek medical consultation regardless of the development of secondary sexual characteristics.