Blood uric acid 444μmol / L, if there is no gout attack, and not combined with diabetes, hypertension and other chronic diseases, then generally do not need to lower uric acid medication; if there is a gout attack, or a combination of diabetes, hypertension and other diseases, then it is recommended to be treated. The diagnostic criterion of hyperuricemia is that the fasting blood uric acid level is greater than 420 μmol/L on two occasions not on the same day. Therefore, blood uric acid 444 μmol/L has already reached the critical value of hyperuricemia, which belongs to the elevation of uric acid level, and it may induce gout, renal function damage, cardiovascular disease and so on. Patients with blood uric acid 444μmol/L need to start treatment with uric acid-lowering drugs if there are gout attacks ≥ 2 times/year, gout stone chronic kidney disease, hypertension, diabetes mellitus, dyslipidemia and other diseases and age of onset <40 years old. Therefore, blood uric acid 444μmol / L, it is recommended that the patient consult a doctor in a timely manner, to check the interference of dietary factors, if necessary, to test blood uric acid again, combined with the underlying disease and other conditions to determine the need for treatment.