Blood in urine after taking lithotripsy drugs is not caused by the drugs, but by the fact that lithotripsy drugs promote the downward movement of stones, which can damage the ureteral mucosa in the process of moving downward and may lead to mucosal bleeding. The hemorrhage is caused by mucosal damage. It is normal for patients with stones to have hematuria, so don’t worry about it. We suggest to continue to drink more water, and at the same time, we should do ultrasound to determine the size and location of the stones. If the stones are relatively small, it is recommended to continue to take lithotripsy medication to promote stone removal. If the stone is larger than 0.5 cm, it is recommended to perform extracorporeal shock wave lithotripsy, so that the possibility of stone discharge will be greater and the risk of bleeding will be reduced.