“Metatarsalgia” is the medical term for metatarsalgia. It is usually seen in the forefoot and can be accompanied by calluses on the soles of the feet, which can recur over time and become corns. “Metatarsalgia is usually divided into two clinical categories: flaccid and compressive. Flaccid metatarsalgia is caused by chronic damage to the transverse arch due to congenital developmental abnormalities of the first bone, and is characterized by primary metatarsal inversion and metatarsal hypermobility. Compressive metatarsalgia is caused by long-term compression of the metatarsal heads by external forces, resulting in long-term compression or irritation of the toe nerves causing interstitial neuritis or neurofibroma. Due to the large size of the metatarsal heads, the gap between the heads is narrower than the gap between the metatarsal stems. The nerve branches passing through this area are vulnerable to injury. When local trauma, strain injury, standing and walking for too long, too much weight, too hard shoes or too high heels, flat feet, etc. can cause damage to the metatarsal heads, affecting the nerves passing through the place, making them thickened, forming nodules, and peripheral tissue hyperplasia, etc., which is the most common at the base of the 3rd and 4th toes. The disease is most common in middle-aged and elderly women between 30 and 50 years of age and in people with narrow, thin and loose feet. Pain and abnormal sensation at the bottom of the forefoot affect standing and walking. The pain is localized or radiates to the toes and can be stabbing, cutting or burning in nature. The pain is so severe that the patient stops standing or walking, removes the shoes and socks, and rubs the area to relieve the pain. In order to avoid pain, patients should wear loose, soft shoes, should not wear high-heeled shoes and shoes with hard soles, avoid standing and walking for too long. Usually, patients can self-massage the bottom of the forefoot, or step on the affected foot on a smooth convex object, rolling and rubbing the forefoot, such as foot massager and other health care products can be used. The patient can take anti-inflammatory and analgesic drugs, such as fenbid, fu-talin, etc., and at the same time with physical therapy, closed, hot compresses, Chinese medicine, external washing can make the symptomatic relief, serious non-healing can go to the regular hospital for consultation and implementation of surgical treatment.