Brittle diabetes is not a name for a disease, but rather an image of the fluctuating blood sugar of some people with diabetes, whose blood sugar goes up and down like a roller coaster. The term “fragile” refers to the fact that blood sugar is very unstable and unusually “fragile”, so that if you eat a little more, your blood sugar goes up, and if you take a little more medicine, you go into a hypoglycemic coma. The first observation of fragile diabetes was in type 1 diabetes, which accounts for about 5% of patients with type 1 diabetes, who are thin and malnourished.
“Fragile diabetes,” also known as “unstable diabetes,” is mainly seen in type 1 diabetes and in some patients with advanced type 2 diabetes with near-islet failure, chronic pancreatitis, and post-pancreatic surgery, and is thought to be caused by complete islet failure. It is thought to be caused by complete islet failure. The patient’s total dependence on exogenous insulin for glycemic control, which is significantly different from physiologic insulin secretion in terms of pharmacogenetics and regulation, and the lack of effective adjunctive regulation, make it easy for blood glucose to fluctuate dramatically from high to low.
The preferred treatment for brittle diabetes is continuous subcutaneous infusion of rapid-acting insulin by an insulin pump, followed by an insulin injection pattern of rapid-acting insulin before three meals and long-acting insulin at bedtime. The first thing you need to do is to use some oral medication (such as metformin, acarbose, etc.) to help “cut the peaks and valleys” and better control sugar.
Because of the extreme fluctuations in blood glucose in fragile diabetes, it is important to pay more attention to diet and exercise, with special emphasis on a regular diet with relatively regular meal times and fewer meals per day, as well as relatively regular and gradual exercise habits, to keep blood glucose within acceptable limits and avoid risks in conjunction with physician treatment.