Diabetic patients with leg weakness consider poor glycemic control, hypokalemia, peripheral neuropathy and other reasons, we need to clarify the cause of the cause of the active treatment, such as peripheral neuropathy can be prescribed by the use of methylcobalamin and other nutritive nerve therapy. 1. Poor glycemic control: poor glycemic control will cause metabolic abnormality in the body, thus causing leg weakness. It is recommended that patients take hypoglycemic drugs such as acarbose, metformin, insulin, etc. to actively control blood glucose according to the doctor’s prescription. 2. Hypokalemia: diabetic patients with hypokalemia will also have symptoms of leg weakness, patients need to follow the doctor’s instructions to use potassium citrate, potassium chloride and other drugs for potassium supplementation therapy. 3. Peripheral neuropathy: long-term hyperglycemia may cause peripheral neuropathy, patients will also show weakness of legs, need to actively control blood glucose at the same time comply with the doctor’s instructions to use methylcobalamin and other nutritive neurological treatment. Diabetic patients with leg weakness need to consult a doctor in time, under the guidance of the doctor to check and treat.