OBJECTIVE: To analyze the bacterial infection spectrum and treatment outcome of abdominal infections in children. METHODS: The isolated bacteria were tested for drug sensitivity by paper diffusion method, and bacterial drug resistance was determined to evaluate the prognosis. RESULTS: A total of 158 pathogenic strains were isolated, and the abdominal cavity infection in children was predominantly G-infection, with the emergence of ultra broad-spectrum p-lactamase (EASBI s)-positive bacteria and resistant strains of all commonly used antibiotics. Surgical treatment is still an effective tool. CONCLUSION: Treatment of abdominal cavity infection in children requires both surgical and antibiotic therapy. Antibiotic therapy requires attention to drug resistance.