Metronidazole gel does not have the effect of getting rid of blackheads. Metronidazole is a kind of antibiotic drug that can be used to treat or prevent systemic or local infections caused by anaerobic bacteria, such as those in the abdominal cavity, lower respiratory tract, female genital system, skin and soft tissues, bones and joints, etc. However, it is not effective in treating black or brown blackheads that occur at the mouth of the hair follicle. Blackheads, also called blackhead pimples, also belong to a type of facial acne and are caused by excessive skin oil secretion, enlargement of the hair follicle opening, oxygen entry where oxidation occurs, the entry of fine dust and the retention of keratin shed by one’s own skin, and are not related to bacteria. The common methods to get rid of blackheads can be divided into physical measures and medication: 1. Physical measures: with the help of a professional physician, the use of blackhead or acne squeezer, or the implementation of acne squeezing method, can effectively get rid of blackheads, after the removal of blackheads follicular pores are still in the open state in the short term, should be combined with the application of vitamin A acid, fruit acid drugs and drugs to shrink pores to avoid the regeneration of blackheads; 2. Medication: because physical measures may For patients with mild symptoms and inconspicuous blackheads, salicylic acid, isotretinoin and other drugs can be used for local application to reduce and control the effect of blackheads. For blackheads covering a large area, the color is obvious, affecting the patient’s normal life, can go to a professional medical beauty hospital using laser treatment to get rid of, at the same time, patients should also pay attention to facial cleaning, sun protection, etc., to prevent excessive secretion of facial oil blocking the follicle pores, thus aggravating the blackheads.