Both hands had a history of eczema for more than 20 years, and the right hand was more serious. At the time of consultation, the patient’s right palm movement was limited, and a thick keratin layer was visible on the palm, accompanied by pustules and oozing, with significant itching. The diagnosis was: eczema with infection. The patient’s family came for follow-up one week later and complained that the patient’s condition was very good and the palm of his hand had returned to normal. After one month, the patient’s family came to the follow-up, on behalf of the patient complained that the patient had started to grow normal nails …… The patient’s life treatment has been greatly improved.