The Japanese named it smog disease based on the morphology of the cerebral angiogram, because the abnormal growth of the vascular network at the base of the skull caused by the narrowing or occlusion of the main arteries in the brain, which looks like a cloud of smoke in the image. Smoke disease can lead to cerebral ischemia, cerebral infarction, cerebral hemorrhage, etc. The specific symptoms can be headache, dizziness, nausea, vomiting, etc. Some patients may have different degrees of consciousness impairment, and may show different degrees of mental retardation, sensory loss, dysphonia, aphasia, migraine, headache, and brain nerve damage. Of course, having this kind of symptoms does not necessarily mean that it is smog, because there may be some other brain diseases that can cause such symptoms. At present, the diagnosis of smog disease usually relies on cerebrovascular imaging, generally CT angiography (CTA), magnetic angiography (MRA), and whole brain angiography (DSA) can be used to diagnose smog disease, among which cerebral angiography is the gold standard for diagnosing smog disease. Cerebral angiography image is clear and high resolution, which provides real three-dimensional images for observation of vascular lesions, localization and measurement of vascular stenosis, diagnosis and interventional treatment, and also provides the basis for subsequent surgical treatment. For the treatment of smog, the more effective surgical procedure is combined vascular bypass surgery, and this advanced procedure has been used to treat smog with excellent clinical results. The combined vascular bypass surgery is different from the direct bypass surgery and the patching surgery, it is done at the same time and on the same stage, so that the blood supply can be improved through the direct bypass while the patching continues to expand the blood supply, which can achieve more ideal results.