The inflection point for female fertility occurs between the ages of 35 and 37, after which fertility gradually declines. Moreover, this age-related decrease in fertility cannot be reversed with the use of drugs. In general, the clinical pregnancy rate is 50% up to age 34, 40% between 35 and 37, 30% between 38 and 39, and 15-20% between 40 and 42; after age 43, the rate of live births is about 3-5%. After the inflection point of fertility, fertility decreases with increasing age and the rate of miscarriage increases, and eventually the rate of live births decreases sharply. Therefore, age is one of the simplest and best indicators of female fertility. For these reasons, older women who need to have children are advised to seek early medical attention and reasonable treatment so as not to miss their last chance to have children. Of course, for married, older women who do not want to have children, embryos can be frozen for fertility preservation.