Men’s chest pain and enlargement may be related to male breast hyperplasia, breast cancer and other reasons. 1. Male breast hyperplasia: a non-tumorigenic, often reversible proliferative response of male breast tissue to sex hormone changes, accounting for more than 82% of male breast lesions. It is manifested by the patient’s feeling that the breast is growing gradually, and a tender lump may be felt under the dark areola. 2. Breast Cancer: It is not rare, a lump appears in the breast, which may gradually increase in size and may cause painful symptoms. It is recommended that men with painful and enlarged breasts go to the hospital in time to clarify the cause of the disease and standardize the treatment under the guidance of the doctor, so as not to bring adverse effects to the body due to the delayed condition.