Difficulties in treatment: a. Very poor visual acuity: often equal to or lower than 0 or 1. Or young children cannot cooperate with visual acuity check. As the training icons around 0,1 provided by the conventional amblyopia treatment instrument are very few, and the fineness of the visual scale changes is small, the children can not see the largest visual enhancement icons or can only see a few of the largest icons, and most of the visual enhancement training icons are in the ineffective state of not being able to see, and the few icons that can be seen can easily be remembered, resulting in boring, poor results and easy to delay the disease. Solution: 1, the use of 0, 01 a 0, 5, fine degree of 0, 002 ~ 0, 004 high-precision threshold visual acuity checklist to find out the threshold visual acuity, and according to the results of the examination, personalized “threshold icon amblyopia treatment instrument”. If you don’t cooperate and can’t find out the visual acuity, you can customize the corresponding “threshold icon amblyopia treatment instrument” according to the visual acuity below 0,05. 2.Additional auxiliary vision enhancement lenses to improve the level of recognition of the threshold visual mark, further reducing the difficulty of improving visual acuity. 3.Wearing far-seeing full correction lenses to fully correct refractive error. Second, the younger the age, poor cooperation: it is known that the younger the age, the better the effect of vision enhancement, but the poorer the cooperation, can not cooperate with the examination and treatment and delay the best time for treatment. 1, <3 years old, can not cooperate, but high sensitivity to vision enhancement training 2, 3-4 years old, can cooperate, but the degree of cooperation is low, there is a higher sensitivity to vision enhancement training 3, >4 years old with a medium degree of cooperation, but sensitivity to vision enhancement training is reduced. From the perspective of cooperation, it is best to check visual acuity before 4 years of age and start high-definition vision enhancement training. Highly myopic amblyopia treatment and examination requires the child’s cooperation with the following items: 1. Threshold visual acuity check: children with visual acuity below 0 or 1 cannot be checked for accurate visual acuity with the ordinary visual acuity table, and must be checked with the “low vision threshold visual acuity table” instead. If you can’t cooperate with the check, the vision below 0,05 will be treated. 2, wearing corrective glasses: full correction of refractive error, wearing glasses is the basis of amblyopia treatment, should pay great attention to, “hard” adhere to 3, amblyopia treatment instrument treatment: because of poor vision, and can cooperate with the use of amblyopia instrument, the age is older, so it is appropriate to more than 3 times a day amblyopia instrument treatment, the course of treatment for at least 1 year. Because the number of training visual markers around 0 or 1 provided by conventional amblyopia therapy instruments is very small, and the fineness of the visual marker changes is low, mostly above 0 or 1, the children can not see the largest visual markers or can only see a few of the largest visual markers, and most of the visual markers for visual enhancement training are in an invalid state of not being able to see, and the few visual markers that can be seen can easily be remembered, resulting in boring and ineffective, and easily delaying the disease. Therefore, it is necessary to customize the high-precision threshold visual marker amblyopia device. 4, a variety of effective methods to control the development of joint 1, the preferred defocus teleopticon and sensitivity teleopticon joint control 2, early use of enhanced myopic control lenses, automatic teleopticon 5, to prevent complications 1, annual ultrasound eye axis and fundus color examination 2, limit high jump, long jump, diving, or basketball, volleyball and other strenuous sports 3, if found with serious degeneration of the fundus, as soon as possible for laser treatment to prevent aggravation 4, to all non-surgical methods of control is not good. 4.Do posterior scleral reinforcement as appropriate for cases not well controlled by all non-surgical methods