The “corns” in the eyes of many people is not a major disease, most may not even have to go to the hospital. Soak your feet, scrape them with a razor blade, and put on a cornsore cream and you’re cured. However, this is not the case for patients with persistent corns, who not only cannot wear leather shoes and walk with a painful limp, but also affect their daily work life and are difficult to cure in the long run. Although laser cautery or surgical removal can be cured, but after all, you need to endure greater pain, to take ten days and a half months off work, spend more medical expenses, like a major disease as the diet and living need to be taken care of. So, what is “corns” about? In layman’s terms, it is a hyperkeratotic lesion that occurs on the abrasive parts of the human foot or hand. There is a growth site at the base of the lesion that produces keratinized tissue, which grows like a nail in the skin and causes pain when pressure is applied to irritate the deeper periosteum or surrounding soft tissue. Since the growth point is deep in the skin, if treated from the surface alone, the phenomenon of “growing and scraping, scraping and growing” will occur, making it difficult to cure. Laser cautery or surgical excision can cause local skin defects, which are easily infected and difficult to heal, seriously affecting daily life. Surgical injection therapy provides a new means for the treatment of stubborn “corns”. It is to inject destructive drugs (such as anhydrous ethanol, phenol glycerin) into the deep “growth point” of the lesion after local anesthesia, so that necrosis occurs gradually from the root, while the integrity of the surrounding tissues and skin is basically not damaged. As long as the “root” is removed, with the gradual natural shedding of the keratinized layer, the lesion will gradually be replaced by normal tissue, and the “corns” will automatically fall off and disappear in a period of time, and the skin will not leave any scars. The most obvious direction of pain is where the root of the lesion is located, but in general the growth point is often directly below the lesion. Routinely disinfect the towel, anesthetize with a 1% lidocaine regional block with a fine puncture needle (skin test needle is sufficient) from the center of the lesion toward the growth point, back off the needle 1 mm after a feeling of falling, and inject 0.2 to 0.3 ml of anhydrous ethanol or phenol glycerin. The sign of successful injection is the blackish purple color of the lesion after one day, and the “corns” will fall off automatically after about 15 to 30 days. Since the injected nerve-destroying drug is irritating to the surrounding normal tissues, there will be mild edema around the lesion for the first few days after the injection, but it usually does not affect daily activities. Since the injection site may sometimes be deviated from the growth point, some patients may need to be re-injected. From the above introduction, we can see that surgical injection therapy for “corns” has the advantages of simple operation, less pain, shorter treatment time, no interference with daily work life, no scar after healing, and low cost.