If a patient has a cramp-like pain in the heart, it is highly considered to be due to a spasm of the coronary arteries, which is considered to be variant angina. For such patients, it is recommended to take drugs like nifedipine tablets or diltiazem tablets to relieve the symptoms, and also in combination with nitrates, such as isosorbide mononitrate or isosorbide nitrate, to further improve the patient’s discomfort. If the patient’s pain symptoms persist for a long time, it is recommended to also check the ECG and cardiac enzymes, to observe whether there is a dynamic evolution of the ECG and whether there are abnormalities in cardiac enzymes. If there are abnormalities in myocardial enzymes or dynamic evolution of the electrocardiogram, it is recommended that the patient should undergo a coronary angiogram in a timely manner. In addition, it may also be caused by cardiac neurosis, especially in patients with severe anxiety or depression, which may lead to cardiac discomfort.