Hcy refers to serum homocysteine in blood tests, a substance produced by the body when digesting proteins, which establishes and maintains the body’s tissue function and directly or indirectly causes vascular endothelial cell damage, promotes the proliferation of vascular smooth muscle cells, affects the oxidation of low-density lipoproteins, increases platelet function and promotes thrombosis. Thus, it can be used for the diagnosis, differential diagnosis and monitoring of cardiovascular diseases and stroke. Normal homocysteine level is <15μmol/L, moderate level is 15-30μmol/L, high level is 30-100μmol/L, and greater than 100μmol/L is a severe excess level. increased Hcy is commonly caused by genetic factors, nutritional factors, drug effects, disease factors, etc. 1. Genetic factors: genetic defects or mutations lead to homocysteine metabolism The lack of enzymes necessary for homocysteine metabolism can cause an increase in homocysteine; 2, nutritional factors: insufficient intake of vitamin B6, vitamin B12, folic acid, etc., can cause homocysteine to accumulate in the body; 3, drug effects: taking anti-epileptic drugs, such as carbamazepine, phenytoin sodium, antibiotics such as methotrexate, asthma drugs such as theophylline, and certain cholesterol drugs, etc., may lead to an increase in homocysteine in the body 4, disease factors: such as heart disease, brain embolism, malignant tumor, kidney failure, liver disease, psoriasis, hypothyroidism, etc., can lead to increased homocysteine; 5, other factors: large intake of coffee, alcohol and other beverages, or smoking and other factors, can lead to increased homocysteine. When a patient's test report shows an increase in homocysteine, the cause needs to be clarified through examination and targeted treatment. It is important to maintain a balanced nutrition on a daily basis by eating more green leafy vegetables, fruits, fish, legumes and grains to help control homocysteine levels in the body. You can also take B vitamins and folic acid to help lower homocysteine.