Large bumps on the legs and arms the more you scratch the more itchy you need to choose drugs according to different causes, may be hives, insect bite dermatitis, eczema and other diseases, can choose from anti-itching agents such as glycerite lotion, hormone creams such as mometasone furoate, anti-allergy drugs such as cetirizine. 1. hives: big bumps on legs and arms, the more you scratch, the more itchy considerations are hives, manifested as raised, itchy skin on the wind. Available glycerine lotion can be applied to stop itching, while antihistamines can be taken, such as loratadine, cetirizine hydrochloride and so on. Treatment should pay attention to find allergens and avoid contact. 2. Mosquito bites: Mosquito bites can also cause bumps on the body with itching symptoms. If the skin is not broken, you can use glycerine lotion to stop itching, apply dieldrin cream to improve itching and swelling symptoms, and prevent infection. If the skin is broken, apply mupirocin ointment to prevent infection. 3. Eczema: Inflammatory reactions occurring due to a variety of internal and external factors, can also appear on the arms and legs big bumps the more you scratch the more itchy situation. At this time, you need to use hormone ointment such as mometasone furoate, oral antihistamine such as loratadine. It is recommended that patients go to the hospital, by the doctor to guide the use of drugs, to avoid self-medication, resulting in adverse effects.