The side effects of long-term use of hemorrhoid cream include drug dependence, allergic reaction to the drug, and miscarriage. 1. produce drug dependence: long-term use of hemorrhoidal cream in the sudden discontinuation of the drug, there will be a recurrence of hemorrhoids or aggravation of the symptoms of hemorrhoids, and again after the use of hemorrhoidal cream to relieve the condition, thus producing dependence. 2. drug allergic reaction: allergic body patients in the use of hemorrhoid cream will appear local redness, swelling, itching or rash and other allergic reactions. 3. triggering miscarriage: some hemorrhoidal cream ingredients may contain musk, pregnant women use, may cause miscarriage, so need to follow the doctor’s instructions for medication. In the use of hemorrhoid cream, must be strictly in accordance with medical advice under the guidance of a doctor, in addition to dietary attention should be paid to eat more food rich in dietary fiber, avoid spicy stimulating food.