The World Health Organization has designated October 28 each year as World Men’s Health Day, calling for worldwide attention to men’s health. Modern men are under a lot of pressure, which not only leads to prostatitis, sexual dysfunction, hair loss, baldness and other male diseases, but also due to the delicate skin of the private parts, local non-ventilation, high humidity, plus the hot weather, which can easily lead to a variety of skin diseases, causing disharmony in family life. The genital area is the most common site for male skin diseases, and the onset of glans penis accounts for the first place, commonly in male patients who are not circumcised. With the increasing number of sexually transmitted diseases (STD) and the improvement of men’s health awareness, the number of patients with genital dermatoses is on the rise, and data show that non-sexually transmitted diseases include non-specific glans vulgaris, pearly papulosis, scrotal eczema, scabies nodules, ringworm, fixed drug rash, glans psoriasis, infectious molluscum contagiosum, vitiligo, angiokeratoma, multiple lipodystrophies, lichen planus, lichen planus, and leucoderma. lichen planus, leucoderma, Bowen-like papulosis, eczema-like carcinoma, etc. Among the diseases clearly related to sexual transmission, condyloma acuminatum was the most common STD, accounting for about one-third of this group, followed by candidal glansitis, genital herpes, syphilis hard chancre, lichen planus, and gonococcal urethritis. The analysis shows that the skin lesions in the genital area are complex and diverse due to the special location, local humidity, and not easy to expose, which often causes patients to delay treatment. In addition, men have more outdoor activities, plus more oil secretion and rougher skin, which are more likely to produce blackheads, acne, hair loss, wrinkles, etc. than women. Therefore, it is especially important for men to clean and care for their skin. The examination methods of genital area skin disease: detailed medical history, including the history of non-marital sexual contact and drug use, as well as physical examination of the whole body, and laboratory tests if necessary, including fungal microscopy, gonococcal smear, white acetate test, dark field examination of syphilis spirochetes and serological examination. Prevention and treatment of skin diseases in the genital area: remove causative factors, actively control primary diseases such as diabetes and kidney disease; keep local skin clean and dry, use skin care lotions and emollients correctly, do not abuse hormonal drugs; clean yourself and have a healthy sex life. Once the skin is found to have uncomfortable symptoms to go to the regular specialist clinic in a timely manner, early diagnosis and treatment.