Once type 2 diabetes is diagnosed, there is a chance to stop the medication permanently, but it is not recommended to stop the medication on your own. Patients should follow their doctor’s advice and keep an eye on their blood glucose so that the disease does not worsen. Type 2 diabetes in remission is defined as a condition in which blood glucose remains on target or normal in the absence of glucose-lowering medication. It is recommended that HbA1c<6.5% be the diagnostic criterion for remission of type 2 diabetes mellitus after stopping glucose-lowering drugs for at least 3 months. Remission of type 2 diabetes mellitus is associated with correction of obesity or significant improvement in body mass, improvement of fatty liver and fatty pancreas, improvement of insulin resistance and hyperinsulinemia, correction of hyperglycemic toxicity, and pancreatic β-cell dedifferentiation and transdifferentiation. It is important to note, however, that after “remission” of type 2 diabetes, even if the measures that led to remission are maintained, blood glucose levels in some patients can rise again to levels that require glucose-lowering medications. Once type 2 diabetes is diagnosed, patients usually need to monitor their blood glucose for the rest of their lives. Patients with type 2 diabetes may experience three excesses and one deficiency, which are excessive eating, drinking, urinating, and weight loss. Type 2 diabetes is mainly treated with insulin, but it can also be treated with glucose-lowering medications such as gliclazide and nateglinide under a doctor’s supervision. Usually, it is necessary to pay attention to diet, regular exercise and regular measurement of blood sugar. When patients with type 2 diabetes experience any physical discomfort, it is recommended that they go to the hospital in time for diagnosis and treatment by a professional doctor.