When the uterus descends from its normal position along the vagina and the external cervical opening reaches below the level of the sciatic spine, or even when the uterus is completely prolapsed outside the vaginal opening, it is called uterine prolapse. Uterine prolapse can occur as a result of injury during pregnancy and childbirth, atrophy and degeneration of the pelvic floor tissue with age, and increased abdominal pressure over time. Treatment of this condition is individualized according to the patient’s age, fertility requirements, degree of prolapse and physical condition. For mild to moderate prolapse, non-surgical treatments such as pelvic floor muscle Kegel training, pelvic floor physical rehabilitation, and uterine support can be used, while for severe prolapse, surgical treatments such as Manchester surgery, total transvaginal hysterectomy, anterior and posterior vaginal wall repair, and vaginal mediastinum formation can be chosen. Uterine prolapse is not self-healing, and prevention is the best strategy as the incidence of this disease is increasing as the life expectancy increases. Women should avoid heavy physical labor (especially after childbirth), arrange rest and work appropriately, actively treat chronic cough and chronic constipation, control weight, prevent excessive and dense childbirth, and advocate regular and effective pelvic floor muscle exercises.