The spinal cord is located in the spinal canal. During human growth and development, the spinal canal grows faster than the spinal cord, so the lower end of the spinal cord gradually rises relative to the lower end of the spinal canal. Spinal cord embolism syndrome is most often seen in newborns and children, but is less common in adults and more common in women than men. In children, the pain is often difficult to localize or located in the lumbosacral region and may radiate to the lower extremities. In adults, the pain is widespread and can be located in the deep anorectum, mid buttocks, tail, perineum, lower extremities and low back, either unilaterally or bilaterally. Pain The nature of pain is mostly diffuse, radiating and electric shock-like pain, but rarely hidden pain. The pain is often aggravated by prolonged sitting and forward flexion of the torso, and rarely by coughing, sneezing and twisting. Progressive weakness and difficulty walking in the lower extremities, and numbness or hypoesthesia of skin sensation. Bladder and rectal dysfunction are often present simultaneously. The former includes enuresis, frequency, urgency, urinary incontinence and urinary retention, while the latter includes constipation or fecal incontinence. In children, enuresis or urinary incontinence is most common.