The efficacy of boron neutrons for non-small cell lung cancer is still under study, and the specific dosage and regimen still need to be further optimized, and the adverse effects need to be further studied. Non-small cell lung cancer is a kind of malignant neoplastic disease of the lung, and its malignant degree is related to the differentiation degree of the tumor. It is often treated clinically with surgical resection, radiotherapy and chemotherapy. Clinically, boride, which is relatively weak in toxicity, is injected into the body to kill tumor cells through intravenous administration to achieve the purpose of treatment. However, its therapeutic effect on non-small cell lung cancer and treatment program still need further research. In addition, boron neutron therapy for tumor has not been widely used yet, and whether to take boride for tumor treatment requires comprehensive assessment by doctors, so patients are advised to go to professional hospitals in time and listen to doctors’ opinions.