Controlled Superovulation and Diet in “IVF” Technique

Why Superovulation Treatment Natural ovulation cycle usually has only one dominant follicle developing and only one embryo can be obtained. Ovulation stimulation cycle uses ovulation stimulating drugs to promote the maturation of multiple eggs at the same time to obtain multiple embryos. The use of controlled superovulation can enhance and improve ovarian function, and can achieve the goal of obtaining multiple eggs without the limitations of the natural cycle, which in turn cultures more embryos and increases the chances of pregnancy What is descending conditioning The use of high-dose gonadotropin-releasing hormone agonists (GnRH-a) in order to cause a state of pituitary desensitization (“descending conditioning”), causing a state of desensitization of the pituitary gland. The purpose of using high-dose gonadotropin-releasing hormone agonist (GnRH-a) to cause pituitary desensitization (“down-regulation”), so that the pituitary gland secretes low levels of gonadotropins (Gn) (this desensitization can be restored by stopping the medication), and then treating it with gonadotropins is to abolish the adverse effects of elevated endogenous luteinizing hormone (LH) or premature peaks in endogenous LH on the quality of the eggs and to stop the follicles from luteinizing prematurely, so as to improve the quality of the eggs, reduce the rate of cycle cancellation, and Increase the success rate of IVF-ET. Purpose of down-regulation Increase sinus follicle recruitment and synchronize follicle development; prevent the premature appearance of endogenous LH peaks and control the time of ovulation; increase the number of eggs obtained and the number of high-quality embryos; improve the endometrial implantation environment. What we need to do before the day of down regulation Prepare the original and photocopy of ID card, marriage certificate, and fertility index; complete all preoperative examinations (including the second semen examination for male comrades); prepare the cash needed for down regulation (about 2,000 RMB) Common techniques of ultra-ovulation monitoring Vaginal ultrasound and blood hormone measurement. Application of the above techniques to track the number of follicles, growth and development of the dynamics of the follicles so as to make a judgment on the development of the follicles, maturity and functional status and to provide the necessary reference information for the prevention of complications of superovulation Abnormal reactions to ovulation Ovarian hyperreactivity and ovarian hyperstimulation signs, young, thin, sensitive to the response of ovulation drugs in the patients, mild and moderate manifestations of nausea and vomiting, bloating and lack of appetite, severe thoracic and abdominal fluid, thrombus formation. fluid in the abdominal cavity, thrombosis, and so on. (Lack of targeted treatment, so the emphasis is on prevention) Ovarian response to poor patients older, the number of follicles after superovulation is less than 3, the cause of ovarian dysfunction. Ovulation promotion time and precautions Punctual and full dosage of medication: The whole process of ovulation promotion takes about 12-15 days, during which the woman should use the ovulation promotion medication at the agreed time, and make sure that the dosage of injection is punctual and full. Increase nutrition: High calorie, high protein, high vitamin, comprehensive and balanced diet, more intake of eggs, milk, soy milk, yogurt, chicken, duck, fish and meat. Please consume a small amount of staple food such as steamed bread or cookies when drinking milk to help digestion and absorption. You can take Jin Shuang Qi and Food Mother’s Life to help digestion and absorption. Common high-protein foods legumes: bean curd, containing 50.5 grams of protein per 100 grams; soybeans, containing 36.3 grams of protein per 100 grams. Mountain products: dried mushrooms, containing 35.6 grams of protein per 100 grams; mushrooms, containing 13.9 grams of protein per 100 grams. Animal offal: pig liver, containing 21.3 grams of protein per 100 grams; meat: lean beef, containing 20.1 grams of protein per 100 grams; beef in sauce, containing 32 grams of protein per 100 grams, braised beef, containing 25 grams of protein per 100 grams. Poultry: chicken, 21.5 grams of protein per 100 grams. Aquatic products: mackerel, containing 19.5 grams of protein per 100 grams; striped bass, containing 18.1 grams of protein per 100 grams; yellow croaker, containing 17.6 grams of protein per 100 grams. Eggs: eggs, containing 14.7 grams of protein per 100 grams; duck eggs, containing 8.7 grams of protein per 100 grams. Ovulation precautions sleep: ensure high quality sleep, such as poor sleep, please make a reasonable work schedule, rest on time every night, drink hot milk before going to bed, hot water foot soak and so on to promote sleep, do not use sleeping sedative drugs without authorization. Emotions: Adjust your mindset, organize your work, cooperate with the examination and treatment calmly, communicate with each other, encourage each other, face difficulties together, and maintain a good state of mind. If you have any questions about the treatment, please ask the doctor in charge in time. Prevention of disease Slight increase of leukorrhea after using the medicine, pay attention to personal hygiene, keep the vulva clean and dry, and at the same time do a good job of vaginal douching and release of medication, wear cotton underwear, do not use pads, to prevent infection. Occasional dry mouth, fever, drowsiness, nausea, mild breast distension and lower abdominal discomfort after using the medicine. As the follicle grows and the ovary enlarges, dress loosely and comfortably, move smoothly and safely, and do not exercise strenuously to avoid ovarian torsion or rupture of the ovary.