Sputum that is yellowish and thick is most commonly associated with inflammatory reactions of the respiratory system in clinical practice. Infected with septic bacterial infections, such as Streptococcus pneumoniae and Staphylococcus aureus, this is a time when symptomatic and etiologic treatment can be directed at these symptoms. For thick sputum, symptomatic treatment can be chosen to remove, dissolve and dilute the sputum. For example, take carboxymethylstilbestrol oral liquid, aminoglutethimide syrup, and granules for clearing lung and resolving phlegm and relieving cough, snake bile Chen Pi San, and snake bile Chuan Bei liquid. For septic bacterial infections, antibiotics such as cefoperazone sulbactam sodium, clindamycin, roxithromycin, and levofloxacin can be chosen.