Hepatogenic diabetes mellitus is a disorder of glucose metabolism secondary to liver disease, and type 2 diabetes mellitus is a primary lesion of the pancreas, which is differentiated in terms of clinical symptoms and blood glucose. Hepatogenic diabetes mellitus and type 2 diabetes mellitus have some similarities, but hepatogenic diabetes mellitus is often secondary to liver disease, and with the recovery of liver function, insulin function can be improved. type 2 diabetes mellitus is primary, and its pathogenesis is related to genetics and environmental factors. In terms of clinical symptoms, hepatic diabetes mellitus usually does not have the typical manifestations of type 2 diabetes mellitus such as polydipsia, polyphagia, polyuria, etc., and is characterized by postprandial blood glucose elevation, which is consistent with the severity of hepatocellular damage. It is recommended to have a medical professional to differentiate and diagnose hepatogenic diabetes mellitus and type 2 diabetes mellitus.