Biopsy of the kidney is an invasive operation, mainly to clarify the pathological changes of the disease. The technical requirements of the operation are relatively high, and the cost of the operation is about 3000~4000 RMB. 1, many diseases require kidney biopsy, mainly nephrotic syndrome, glomerulonephritis of unknown etiology, acute nephritis syndrome, hematuria of non-glomerular origin that cannot be excluded by various examinations, renal hypertension of unknown origin, acute renal failure, etc. The significance of biopsy is mainly to clarify the diagnosis and guide the treatment through the results of puncture biopsy, and also to assess the prognosis of the patient. 2, kidney biopsy also has its contraindications, such as obvious bleeding tendency, severe hypertension, isolated kidney. For renal abscess and renal tuberculosis, they are relative contraindications. 3, kidney biopsy after surgery must strengthen the care, pay attention to observe the patient’s vital signs, every half hour to measure the blood pressure. Wait for the condition to stabilize, you can properly move to the ground, drink more water after surgery, try to exclude the clot, pay more attention to rest. The diet should be light and easy to digest to prevent wound infection and secondary bleeding. The technical level of kidney biopsy is demanding, so it is best to go to the nephrology department of a tertiary general hospital for treatment.