For acute pseudomembranous candidiasis (thrush or neonatal xerostomia), lips, cheeks, tongue and palate can be involved, extensive congestion on the mucous membrane, covered with small white spots or pseudomembrane, a little force can be wiped off, revealing the congested side of the child manifested as drooling and refusal to eat. Treatment: Generally, local 2% sodium bicarbonate solution can be used to clean the children’s mouth 3 times/day. For serious condition, systemic use of antifungal drugs can be considered. The medication cycle is long, even after the disappearance of symptoms, still need to adhere to the medication 7 – 14 days, to avoid recurrence; infant patients should avoid cross-infection, pay attention to maternal nipple cleaning (1: 5000 chlorohexidine solution cleaning, and then wash with water); pay attention to prohibit the use of glucocorticosteroids.