China is the homeland of wine and the birthplace of wine culture, and the five thousand years of China is a history of wine. Wine is a good thing, friends meet, you can “open a jug of wine, sip on the spring breeze”; friends and family banquet, active atmosphere, you can “cook sheep and slaughter cattle and for fun, will have to drink a 300 cups”; lost, you can ” When you are disappointed, you can “get drunk today, tomorrow’s sorrow will be tomorrow’s worry”, no wonder the ancients said “nine turns of elixir that save wine?” The “drunkenness is lighter than the king”. Wine is also a bad thing, it will harm our health. When it comes to the dangers of alcohol, many people know that the liver can break down alcohol, but if you drink too much alcohol, it will hurt your liver. But most people may not know that alcohol abuse not only hurts the liver but also the bone, and in recent years, cases of femoral head necrosis caused by alcohol abuse have been common. There is a patient 33 years old, due to the nature of work often deal with wine, this year after the Spring Festival, feel a little pain in the root of the thigh, then thought it was due to lack of exercise. 4 months later, the pain worsened, activity is limited, the patient almost paralyzed in bed, after diagnosis, for stage 3 femoral head necrosis. First, wine is a blood activator, why does it lead to femoral head necrosis? Long-term alcohol consumption will cause disorders of fat metabolism in the body, elevating blood lipids, fibrous degeneration and atherosclerosis of small arteries, and serious damage to cell membranes, leading to local ischemia of the femoral head; increased fat in the blood will gather into fat globules, making the microvessels under the cartilage of the femoral head embolized, and the femoral head will not be nourished, leading to ischemic necrosis of the femoral head; alcohol and its metabolites have a direct cytotoxic effect, which will make ischemic Alcohol and its metabolites have direct cytotoxic effects, which can cause ischemia, hypoxia, degeneration and necrosis of bone cells, leading to aseptic necrosis of the femoral head. Second, “not drunk” need not worry about femoral head necrosis to “mess up”? Some people think that they can drink a lot of alcohol, and drink white wine like boiling water, so they are nicknamed “a thousand glasses of intoxication”, so the disease of bone “drunkenness” has nothing to do with “me”. I advise those who think so to sober up! As a matter of fact, femoral head necrosis has nothing to do with the size of the wine, there are congenital factors, mainly related to acetaldehyde enzyme, the high decomposition of this enzyme is very fast, the amount of wine is large. Ischemic necrosis of the femoral head is most willing to look for “a thousand glasses of wine”, such as a day to drink more than half a kilogram of alcoholics. In general, if you drink a lot of alcohol every day, you may have femoral head necrosis in about ten years. However, there are individual differences, in the clinic, some patients do not drink much, the bones also ‘drunken death’. In addition, if there is someone in the family who has suffered from femoral head necrosis due to drinking, there is a family tendency to develop the disease.