There is no such thing as a nevus of melanoma that is best not to be removed, and the decision should also be based on the location, and whether there is any malignant change. Nevus melanosus is a benign skin tumor of melanocyte origin, which can be classified as congenital and acquired, and can occur in any part of the skin. Depending on the depth of the nevus, it can be categorized as junctional nevus, compound nevus, or intradermal nevus. Generally, nevi do not need special treatment. If it occurs in palm and plantar, waist, armpit, groin and other parts of the body that are easily irritated by friction, surgical excision should be considered. Those with malignant tendency should be excised as early as possible, and at the same time, pathological histologic examination should be done. Specific cases should also go to the hospital for examination before deciding on the treatment plan.