Nephrotic syndrome is a clinical syndrome caused by increased permeability of the glomerular filtration membrane to plasma proteins, resulting in a large amount of plasma proteinemia lost from the urine, leading to a series of pathophysiological changes. Its main clinical features are massive proteinuria, hypoproteinemia, hyperlipidemia and edema. The syndrome is a common glomerular disease in pediatrics and is often recurrent or relapsing during the course of the disease, which seriously affects the health of the child. In the process of treatment and rehabilitation of nephrotic syndrome, in addition to standardized drug therapy, reasonable nutritional therapy is also crucial. Excessive intake of nutrients will increase the burden on the kidneys and accelerate the deterioration of the disease, and conversely, insufficient intake of nutrients will lead to malnutrition and growth retardation. Therefore, reasonable nutritional treatment becomes the focus of attention of doctors and parents. As we all know, carbohydrates, fats, proteins, vitamins, water and inorganic salts (minerals) are the six major nutrients required by the human body. The reasonable nutrition of children with nephrotic syndrome is closely related to these six nutrients. 1, carbohydrates: is the body’s main source of calories, involved in many life activities, is a component of the cell membrane, maintain normal nerve supply, promote the metabolic role of fat, protein in the body. For children with kidney disease, carbohydrate intake should account for 55% to 65% of the energy, of which 50% more sugar and dietary fiber. 2, protein: If the human body is treated as a building, then protein is the building materials that make up the building. Children with nephrotic syndrome, a large amount of plasma protein excreted from the urine, the human body protein is reduced and in a state of protein malnutrition, the body resistance is also reduced, but, despite this, it is not recommended to give children a high protein diet, but should be based on high quality high protein, to 1,0 ~ 1,5g/kg, d is appropriate, of which animal protein accounted for 2/3 (such as eggs, milk, lean meat, fish, etc.), vegetable protein This helps to alleviate the hypoproteinemia and some comorbidities caused by it. However, in children with impaired renal function, protein intake should be limited, and low protein 0.8-1.2 g/kg? d can be given as appropriate, and mainly high-quality protein. 3, fat: because children with nephrotic syndrome are often accompanied by hyperlipidemia, which can aggravate proteinuria and glomerular damage, and promote glomerulosclerosis, so the intake of fat should be limited. Fat intake should be controlled within 30% of energy, should be less into the diet rich in saturated fatty acids (animal fats), and eat more diet rich in polyunsaturated fatty acids such as fish oil, vegetable oil, etc. can make the blood lipid drop and urine protein reduction, glomerulosclerosis reduced, diet rich in soluble fiber (oats, rice bran, etc.) is also conducive to lowering fat. Foods rich in saturated fatty acids: animal fats, such as butter, lamb fat and lard; a few vegetable oils: coconut oil, cocoa butter, palm oil; foods rich in unsaturated fatty acids: fish oil; most vegetable oils, such as flaxseed oil, tea oil, sunflower oil, etc.; nuts: walnuts, almonds, pine nuts, etc. 4, vitamins and minerals: due to the increased permeability of the glomerular basement membrane in children with nephrotic syndrome, in addition to the loss of a large amount of protein in the urine, but also the loss of certain trace elements combined with protein, should be given appropriate supplements. Generally, you can eat vitamins and trace elements rich vegetables, fruits, grains, seafood, etc. to supplement vitamin B, C, D and folic acid and iron, copper, zinc, etc.