Diabetic phytoneuropathy is firstly to stabilize blood glucose, and then to use the drugs of nutritive nerves and drugs of improving microcirculation. 1. Active control of blood glucose: diabetes-induced phytoneuropathy first needs active control of blood glucose. Patients should use drugs such as metformin, glimepiride, repaglinide, acarbose and insulin to control blood sugar under doctor’s instruction. In addition, diet control and active exercise are also needed. 2. Nutritional nerve drugs: including methylcobalamin, lipoic acid, epoprostenol and other drugs. 3. Drugs to improve microcirculation: Generally there are Ginkgo biloba extract, pancreatic kininogenase, bezprolium, etc., which can improve microcirculation and blood supply of local nerves. Diabetic phytoneuropathy generally has gastrointestinal, cardiovascular and genitourinary symptoms. Possible clinical manifestations include delayed gastric emptying, diarrhea, constipation, tachycardia, upright hypotension, urinary incontinence or retention, abnormal sweating, and decreased sexual function. If diabetic phytoneuropathy is present, it is recommended to seek medical attention and use medication under the supervision of a doctor.