Catheter-associated bloodstream infection is defined as a patient with an intravascular catheter or within 48 hours of removal of an intravascular catheter who develops bacteremia or fungemia with manifestations of infection such as fever (temperature >38°C), chills or hypotension, with no clear infectious agent other than the catheter, and the microorganisms cultured at the catheter tip are consistent with the microorganism results of blood cultures. The factors associated with catheter-associated bloodstream infections are mainly the lack of strict hand disinfection of the operator, as well as the material of the catheter, the site of retention, and also associated with the patient’s own skin contamination and immune deficiency, whose preventive measures are mainly to ensure the maximum sterile barrier during operation, to strictly enforce hand hygiene, and to choose the ideal placement position and to evaluate the catheter daily after placement.