The foramen ovale is the most common congenital heart disease in adults. Under normal circumstances, the foramen ovale usually closes within the first year of life. If the foramen ovale remains unclosed in children older than three years of age, the diagnosis of unclosed foramen ovale heart disease can be made. The foramen ovale does not close completely in about 20-25% of adults, and foramen ovale is by far the most common congenital cardiac anomaly in adults. It has long been thought that foramen ovale insufficiency does not normally cause blood shunting between the two atria and has no significant effect on the hemodynamics of the heart, nor does it cause significant clinical symptoms, so it was thought that foramen insufficiency did not require special treatment. However, studies have demonstrated a close relationship between patent foramen ovale and patients with unexplained stroke, probably because emboli can enter the neural circulation through the patent foramen ovale and cause the corresponding clinical symptoms.