Neonatal patent foramen ovale is relatively common and most babies heal on their own at around 6 months of age. Neonatal patent foramen ovale is a physiological phenomenon. Normally, functional closure of the foramen ovale occurs after birth with crying and pulmonary function, but complete anatomical closure does not occur until after 6 months of age and no later than 1 week of age. Therefore, if the foramen ovale is not closed during the neonatal period, no special treatment is usually needed if there are no other cardiac anomalies combined. However, if the foramen ovale is still not closed after 1 week of age, the baby needs to be seen for evaluation. In newborns with unclosed foramen ovale, regular review is recommended, which can be done at 3 months, 6 months and 12 months of age, to watch for signs of closure.