Hemorrhoids are not cancerous, but if left untreated, they may indirectly increase the risk of bowel cancer. In addition, the similarity between hemorrhoids and rectal cancer symptoms can lead to recurrent bleeding that can be mistaken for hemorrhoids. When bleeding in the stool occurs and is recurrent, it should be taken seriously, and attention should be paid to the differential diagnosis. Hemorrhoidal blood in stool can be caused by the patient’s abrasion of hemorrhoids during defecation, which is usually manifested as blood on the surface of stool, blood dripping during defecation, blood on the paper after defecation, etc., and the color of blood in stool is mostly bright red; rectal cancer blood in stool can be caused by the bleeding or oozing of blood due to the breakage of the tumor surface, and the color of the blood is mostly dark red or jam color, or even black, and it also comes with mucus and pus. It is suggested that patients should actively go to anorectal department for rectal fingerprint examination. If the tumor at the upper end of the rectum is difficult to be detected, enteroscopy can be used to make a clear diagnosis if necessary.