Usually, it is safest to stop taking conventional anti-inflammatory drugs for 3 months before pregnancy. There are many different types of anti-inflammatory drugs in routine clinical use, and any drug has side effects and a certain metabolic period. Most anti-inflammatory drugs can interfere with conception or cause abnormal fetal development early on, and may even lead to miscarriage. Women of childbearing age preparing for pregnancy must wait until the drug components are completely broken down and metabolized and excreted in the body before they can consider pregnancy. The metabolism time of anti-inflammatory drugs in the body varies depending on the type of drug, the dose taken and the total time of taking the drug, with most taking 14-30 days and individual drugs taking more than 3 months to be completely metabolized. The specific situation needs to be decided by a medical professional according to the specific type of medication. During pregnancy preparation, oral folic acid can be taken to avoid fetal neurodevelopmental malformations. Also keep a happy mood and avoid indiscriminate use of medications.