Syphilis is a venereal infection. At the second stage of syphilis there is a characteristic manifestation called syphilis rash, which can be found on the skin and mucous membranes of the whole body and even on the palms of the hands and soles of the feet, which is the characteristic manifestation of syphilis, and individual patients will have the phenomenon of pustules, which usually disappear in 2 to 3 months.
It is worth noting that blisters on the soles of the feet are all just a common manifestation of syphilis; diseases such as ringworm, eczema, aspergillosis or hand, foot and mouth disease can also cause it to occur, so proper medical attention is needed to diagnose it.