Men with vague pain in the lower abdomen do not necessarily have cancer, because in addition to cancer, other diseases may also lead to vague pain in the lower abdomen. Men’s lower abdominal pain can be seen in appendicitis, ulcerative colitis, acute enteritis, prostatitis, ureteral calculi and many other diseases. Appendicitis is mainly pain in the right lower abdomen; and prostatitis is mainly pain in the perineum or on the pubic bone, with symptoms such as frequent and urgent urination. However, it is true that cancer may also manifest as vague pain in the lower abdomen, for example, bowel cancer is a common type of cancer in daily life, mostly seen among middle-aged and elderly men. In addition to vague pain in the lower abdomen, patients may also have symptoms such as blood in the stool, urgency, diarrhea and constipation, which can usually be distinguished by going to the hospital for colonoscopy or CT examination. Therefore, men with long-term lower abdominal pain are still recommended to go to the hospital for timely examination and choose the appropriate treatment for different conditions.