The degree of risk of frequent premature ventricular contractions depends on the patient’s specific condition. It is more dangerous if the patient has underlying heart disease, but not life-threatening if the patient only has premature contractions and mild symptoms. Frequent premature ventricular contractions are defined as premature ventricular contractions that occur more than five times a minute. However, the degree of risk is not only based on the number of premature contractions, but also on whether the patient has an underlying heart condition. Frequent ventricular premature beats are more dangerous if the patient has organic heart disease such as coronary artery disease, cardiomyopathy, hypertensive heart disease, and rheumatic heart disease. Drug therapy with antiarrhythmic drugs beta-blockers such as metoprolol, nondihydroarsenoid calcium channel blockers such as verapamil and diltiazem, and propafenone is usually required, along with aggressive treatment for the primary heart disease. Patients with frequent ventricular premature beats who do not have organic heart disease usually do not need medication if they only experience some symptoms of panic. Patients with frequent ventricular premature beats need to undergo regular follow-up with an ambulatory electrocardiogram (ECG) to observe changes in heart rhythm and heart rate over a 24-hour period, which will facilitate the next step in diagnosis and treatment.