Almost everyone will have at least one scar in their lifetime. Young mothers who have just reaped the joy of childbirth are often bothered by the ugly appearance of the linear scar from the cesarean section, young and beautiful girls are depressed because they cannot wear bathing suits because they have appendectomy scar, talented and flamboyant teenagers are often upset because of the acne pits on their faces that affect finding a girlfriend, and parents of children who have been burned by hot water on the face and neck are worried about the disfigurement caused by the burns. All these troubles are related to scarring. Moderate repair leads to wound healing, while excessive repair leads to the formation of pathological scar, causing disfigurement and functional impairment of varying degrees. Pathological scarring often occurs after surgery, trauma, burns, and inflammation, and has a high incidence. The histological characteristics are massive fibroblast proliferation, excessive deposition of collagen, proteoglycans, and glycoproteins in the extracellular matrix, and disorganized collagen fiber arrangement. Its clinical manifestations are abnormal sensation, verrucous hyperplasia with varying degrees of dysfunction. During the long period of maturation and treatment of scarring, millions of patients suffer from persistent symptoms and dysfunction, which are psychologically and physically harmful to patients. The treatment methods for scarring can be described as diverse, and the previous treatment methods include hormone injection in the scar, compression therapy, anti-tumor drug therapy, cytokine-related therapy, silicone gel coverage, cryotherapy, radiotherapy, etc., but the efficacy is not satisfactory: or the side effects are more, such as local normal tissue necrosis, pigmentation or hypopigmentation, endocrine disorders, etc., which are difficult for patients to accept; or the use is inconvenient, and the patient’s compliance is seriously affected. It is not easy to promote and the efficacy is poor. The surgical treatment mainly based on scar release, flap transplantation or scar excision implantation is mainly aimed at improving the function of the scar with serious impact, which is more traumatic and has limited effect on improving the appearance of the scar; the treatment effect on the large area of non-functional scar (such as burn scar) is even more limited, and cannot meet the clinical effect of minimally invasive, convenient, and satisfactory in function and appearance at the same time, so scar is still a Therefore, scarring is still a difficult problem in burn trauma therapeutics. To meet the requirements of minimally invasive treatment, a range of laser treatments have been applied to scar treatment for many years. Fractional laser technology was introduced in 2006 and is based on the theory of Fractional Photothermolysis, which was proposed by Rox Anderson, an expert in photomedicine at Harvard University, in 2004, and is an alternative to the traditional Selective Photothermolysis. FractionalPhotothermolysis is an extension of the traditional SelectivePhotothermolysis. The principle of action is to convert a laser beam or light into many tiny beams through a filter, and each beam acts on the epidermis and/or scar to form a central exfoliative zone and a surrounding thermal coagulation zone to form a microscopictreatment zone (MTZ). In turn, the tissue initiates a “trauma repair mechanism”, which leads to an increase in collagen synthesis within the scar and an orderly arrangement of new collagen. The skin around the microscopic pores remains intact, and the preserved skin acts as a “bridge” during the repair, allowing the repair to be completed more quickly. The stratum corneum is largely restored 24 hours after treatment. In 2009, Haedersdal first applied the CO2 fractional laser to a 42-year-old male with burn scarring. 3 months after treatment, the skin texture and color improved significantly on the forearm side using a high-energy microthermal zone, and the skin was flatter and smoother than on the untreated side. Subsequently, some scholars tried the CO2 fractional laser in the treatment of patients with post-burn scars on the chest with obvious results; some literature reported that in the treatment of 98 cases of various types of hyperplastic scars (including 60 cases of burn scars), its total effective rate reached 100%, and the apparent rate was 83.33%; for patients with old scars with burns over 50 years old, the exfoliative CO2 fractional laser was also effective. The latest ultra-pulsed CO2 fractional laser can be adjusted in energy and density to obtain microthermal treatment zones of different shapes, depths and treatment densities, allowing for individualized treatment plans for different scar conditions, thus achieving optimal results while significantly reducing the side effects of laser treatment. In 2013, eight experienced scar specialists, led by Professor Dr. Rox Anderson, director of the Wellman Center for Photomedicine and founder of the fractional photothermolysis theory of action at Harvard Medical School, completed a consensus on scar treatment after two years of clinical experience. The consensus concluded that laser treatment of scars, especially ablative fractional laser treatment, is a very promising but underutilized tool for the comprehensive treatment of traumatic scars. Changes in existing scar treatment protocols should include extensive integration of fractional skin reconstruction techniques and other combination treatment options. The ablative CO2 fractional laser has a large number of successful clinical cases and studies in scar treatment both nationally and internationally due to its use. Stories of this technology helping countless scar patients revive their lives are circulating around the world, such as the triplet sisters in the United States, who were burned by a fire when they were 3 years old and had extensive moderate to severe scars all over their bodies. More than 20 years later, they saw on TV that a doctor in Miami was using Lumenis’ ultra-pulsed CO2 laser to treat scars with excellent results, and they drove from California to Miami. They drove from California to Miami to find this doctor, and after multiple treatments, they described their skin as smoother and softer, and they felt reborn! Since then, they have set up the Triplet Sisters Foundation to help those scarred by the fires. In addition to removing scars and improving their appearance, functional improvements are helping more people to live better lives.